Protective effects of macrophage-specific integrin α5 in myocardial infarction are associated with accentuated angiogenesis

Protective effects of macrophage-specific integrin α5 in myocardial infarction are associated with accentuated angiogenesis

Abstract Macrophages sense changes in the extracellular matrix environment through the integrins and play a central role in regulation of the reparative response after myocardial infarction. Here we show that macrophage integrin α5 protects the infarcted heart from adverse remodeling and that the pr...

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Bibliographic Details
Main Authors: Ruoshui Li, Bijun Chen, Akihiko Kubota, Anis Hanna, Claudio Humeres, Silvia C. Hernandez, Yang Liu, Richard Ma, Izabela Tuleta, Shuaibo Huang, Harikrishnan Venugopal, Fenglan Zhu, Kai Su, Jun Li, Jinghang Zhang, Deyou Zheng, Nikolaos G. Frangogiannis
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43369-x

Internet

https://doi.org/10.1038/s41467-023-43369-x

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