Replication independent DNA double-strand break retention may prevent genomic instability
<p>Abstract</p> <p>Background</p> <p>Global hypomethylation and genomic instability are cardinal features of cancers. Recently, we established a method for the detection of DNA methylation levels at sites close to endogenous DNA double strand breaks (EDSBs), and found t...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-03-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/70 |