Acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA

Acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA

Acetyl and other acyl groups from different short-chain fatty acids (SCFA) competitively modify histones at various lysine sites. To fully understand the functional significance of such histone acylation, a key epigenetic mechanism, it is crucial to characterize the cellular sources of the correspon...

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Bibliographic Details
Main Authors: Nour Zeaiter, Laura Belot, Valérie Cunin, Roland Abi Nahed, Malgorzata Tokarska-Schlattner, Audrey Le Gouellec, Carlo Petosa, Saadi Khochbin, Uwe Schlattner
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Molecular Metabolism
Subjects:
Acyl-CoA
Epigenetics
Histone acylation
Protein acylation
Substrate specificity
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824000346

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http://www.sciencedirect.com/science/article/pii/S2212877824000346

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