Evaluation of Cell-Specific Alterations in Alzheimer’s Disease and Relevance of In Vitro Models

Alzheimer’s disease (AD) is a neurodegenerative disorder classically characterized by two neuropathological hallmarks: β-amyloid plaques and tau tangles in the brain. However, the cellular and molecular mechanisms involved in AD are still elusive, which dampens the possibility of finding new and mor...

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Bibliographic Details
Main Authors: Giorgio Guido, Katia Mangano, Lyubka Tancheva, Reni Kalfin, Gian Marco Leone, Andrea Saraceno, Paolo Fagone, Ferdinando Nicoletti, Maria Cristina Petralia
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/14/12/2187