High G2M Pathway Score Pancreatic Cancer is Associated with Worse Survival, Particularly after Margin-Positive (R1 or R2) Resection

High G2M Pathway Score Pancreatic Cancer is Associated with Worse Survival, Particularly after Margin-Positive (R1 or R2) Resection

Pancreatic cancer is highly mortal due to uncontrolled cell proliferation. The G2M checkpoint pathway is an essential part of the cell cycle. We hypothesized that a high G2M pathway score is associated with cell proliferation and worse survival in pancreatic cancer patients. Gene set variation analy...

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Bibliographic Details
Main Authors: Masanori Oshi, Stephanie Newman, Yoshihisa Tokumaru, Li Yan, Ryusei Matsuyama, Itaru Endo, Matthew H. G. Katz, Kazuaki Takabe
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
biomarker
cell cycle
gene set
pathway analysis
pancreatic cancer
tumor gene expression
Online Access:https://www.mdpi.com/2072-6694/12/10/2871

Internet

https://www.mdpi.com/2072-6694/12/10/2871

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