Germline Mutation Landscape and Associated Clinical Characteristics in Chinese Patients With Renal Cell Carcinoma

Germline Mutation Landscape and Associated Clinical Characteristics in Chinese Patients With Renal Cell Carcinoma

BackgroundRenal cell carcinoma (RCC) is a disease of genomic alterations, of which the complete panorama helps in facilitating molecular-guided therapy. Germline mutation profiles and associated somatic and clinical characteristics remains unexplored in Chinese RCC patients.MethodsWe retrospectively...

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Bibliographic Details
Main Authors: Wen Kong, Tongtong Yang, Xiaodong Wen, Zhongyi Mu, Cheng Zhao, Sujun Han, Jing Tian, Xinhao Zhang, Tao Zhou, Yanrui Zhang, Feng Lou, Shanbo Cao, Huina Wang, Jin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Oncology
Subjects:
renal cell carcinoma
germline mutations
Chinese population
pathogenic variation
second hit events
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.737547/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.737547/full

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