Ultrasound-targeted microbubble destruction promotes PDGF-primed bone mesenchymal stem cell transplantation for myocardial protection in acute Myocardial Infarction in rats

Ultrasound-targeted microbubble destruction promotes PDGF-primed bone mesenchymal stem cell transplantation for myocardial protection in acute Myocardial Infarction in rats

Abstract Background Ultrasound-targeted microbubble destruction (UTMD) has emerged as a promising strategy for the targeted delivery of bone marrow mesenchymal stem cells (MSCs) to the ischemic myocardium. However, the limited migration capacity and poor survival of MSCs remains a major therapeutic...

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Bibliographic Details
Main Authors: Zhenxing Sun, Yu Cai, Yihan Chen, Qiaofeng Jin, Ziming Zhang, Li Zhang, Yuman Li, Lei Huang, Jing Wang, Yali Yang, Qing Lv, Zhengyang Han, Mingxing Xie, Xiangming Zhu
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Journal of Nanobiotechnology
Subjects:
Ultrasound-targeted microbubble destruction
Bone mesenchymal stem cells
Acute Myocardial Infarction
PDGF-BB
Online Access:https://doi.org/10.1186/s12951-023-02204-7

Internet

https://doi.org/10.1186/s12951-023-02204-7

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