Whole-genome analysis of monozygotic Brazilian twins discordant for type 1 narcolepsy: a case report

Whole-genome analysis of monozygotic Brazilian twins discordant for type 1 narcolepsy: a case report

Abstract Background Narcolepsy type 1 (NT1) is a rare and chronic neurological disease characterized by sudden sleep attacks, overwhelming daytime drowsiness, and cataplexy. When associated with a sudden loss of muscle tone (cataplexy) narcolepsy is classified as type 1, while the absence of cataple...

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Bibliographic Details
Main Authors: João H. C. Campos, Ana C. R. Aguilar, Fernando Antoneli, Giselle Truzzi, Marcelo R. S. Briones, Renata C. Ferreira, Fernando M. S. Coelho
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Neurology
Subjects:
Narcolepsy type 1
Whole-genome analysis
HLA
Autoimmune disease
Discordant monozygotic twins
Diagnostics
Online Access:https://doi.org/10.1186/s12883-022-02921-w

Internet

https://doi.org/10.1186/s12883-022-02921-w

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