GTax: improving de novo transcriptome assembly by removing foreign RNA contamination

Abstract The cost and complexity of generating a complete reference genome means that many organisms lack an annotated reference. An alternative is to use a de novo reference transcriptome. This technology is cost-effective but is susceptible to off-target RNA contamination. In this manuscript, we p...

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Bibliographic Details
Main Authors: Roberto Vera Alvarez, David Landsman
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-023-03141-2