Obesity Associated with Prediabetes Increases the Risk of Breast Cancer Development and Progression—A Study on an Obese Rat Model with Impaired Glucose Tolerance

Obesity Associated with Prediabetes Increases the Risk of Breast Cancer Development and Progression—A Study on an Obese Rat Model with Impaired Glucose Tolerance

Patients with comorbidities of obesity and diabetes are recognized to be at high risk of breast cancer development and face worse breast cancer outcomes. Though several reports showed the reinforced link between obesity, diabetes, and prediabetes with breast cancer, the underlying molecular mechanis...

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Bibliographic Details
Main Authors: Prathap Reddy Kallamadi, Deepshika Esari, Utkarsh Reddy Addi, Rushendhiran Kesavan, Uday Kumar Putcha, Siddavaram Nagini, Geereddy Bhanuprakash Reddy
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:International Journal of Molecular Sciences
Subjects:
breast cancer
obesity
metabolic syndrome
obese rat model
DMBA
insulin signaling
Online Access:https://www.mdpi.com/1422-0067/24/14/11441

Internet

https://www.mdpi.com/1422-0067/24/14/11441

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