An Adaptation to Low Copper in Candida albicans Involving SOD Enzymes and the Alternative Oxidase.

In eukaryotes, the Cu/Zn superoxide dismutase (SOD1) is a major cytosolic cuproprotein with a small fraction residing in the mitochondrial intermembrane space (IMS) to protect against respiratory superoxide. Curiously, the opportunistic human fungal pathogen Candida albicans is predicted to express...

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Bibliographic Details
Main Authors: Chynna N Broxton, Valeria C Culotta
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5198983?pdf=render