Transcriptional profiling of canine osteosarcoma identifies prognostic gene expression signatures with translational value for humans

Abstract Canine osteosarcoma is increasingly recognized as an informative model for human osteosarcoma. Here we show in one of the largest clinically annotated canine osteosarcoma transcriptional datasets that two previously reported, as well as de novo gene signatures devised through single sample...

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Bibliographic Details
Main Authors: Joshua D. Mannheimer, Gregory Tawa, David Gerhold, John Braisted, Carly M. Sayers, Troy A. McEachron, Paul Meltzer, Christina Mazcko, Jessica A. Beck, Amy K. LeBlanc
Format: Article
Language:English
Published: Nature Portfolio 2023-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05208-z