A general method for determining secondary active transporter substrate stoichiometry

The number of ions required to drive substrate transport through a secondary active transporter determines the protein’s ability to create a substrate gradient, a feature essential to its physiological function, and places fundamental constraints on the transporter’s mechanism. Stoichiometry is know...

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Bibliographic Details
Main Authors: Gabriel A Fitzgerald, Christopher Mulligan, Joseph A Mindell
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/21016