MicroRNAs and Osteoarthritis

An imbalance in gene expressional events skewing chondrocyte anabolic and catabolic pathways toward the latter causes an aberrant turnover and loss of extracellular matrix proteins in osteoarthritic (OA) articular cartilage. Thus, catabolism results in the elevated loss of extracellular matrix prote...

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Bibliographic Details
Main Author: Charles J. Malemud
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/7/8/92