Structure-Activity Relationships of Bioengineered Heparin/Heparan Sulfates Produced in Different Bioreactors

Structure-Activity Relationships of Bioengineered Heparin/Heparan Sulfates Produced in Different Bioreactors

Heparin and heparan sulfate are structurally-related carbohydrates with therapeutic applications in anticoagulation, drug delivery, and regenerative medicine. This study explored the effect of different bioreactor conditions on the production of heparin/heparan sulfate chains via the recombinant exp...

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Bibliographic Details
Main Authors: Ha Na Kim, John M. Whitelock, Megan S. Lord
Format: Article
Language:English
Published: MDPI AG 2017-05-01
Series:Molecules
Subjects:
heparin
heparan sulfate
serglycin
proteoglycan
recombinant expression
bioreactor
Online Access:http://www.mdpi.com/1420-3049/22/5/806

Internet

http://www.mdpi.com/1420-3049/22/5/806

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