Follistatin-like 1 promotes proliferation of matured human hypoxic iPSC-cardiomyocytes and is secreted by cardiac fibroblasts

Follistatin-like 1 promotes proliferation of matured human hypoxic iPSC-cardiomyocytes and is secreted by cardiac fibroblasts

The human heart has limited regenerative capacity. Therefore, patients often progress to heart failure after ischemic injury, despite advances in reperfusion therapies generally decreasing mortality. Depending on its glycosylation state, Follistatin-like 1 (FSTL1) has been shown to increase cardiomy...

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Detalles Bibliográficos
Main Authors: Marijn C. Peters, Sofia Di Martino, Thomas Boelens, Jiabin Qin, Alain van Mil, Pieter A. Doevendans, Steven A.J. Chamuleau, Joost P.G. Sluijter, Klaus Neef
Formato: Artigo
Idioma:English
Publicado: Elsevier 2022-06-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
Follistatin-like 1
iPSC-cardiomyocytes
ischemic heart disease
hypoxia
fibroblasts
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2329050122000213

Internet

http://www.sciencedirect.com/science/article/pii/S2329050122000213

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