Development of a Predictive Dosing Nomogram to Achieve PK/PD Targets of Amikacin Initial Dose in Critically Ill Patients: A Non-Parametric Approach
French guidelines recommend reaching an amikacin concentration of ≥8 × MIC 1 h after beginning infusion (C<sub>1h</sub>), with MIC = 8 mg/L for probabilistic therapy. We aimed to elaborate a nomogram guiding clinicians in choosing the right first amikacin dose for ICU patients in septic...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-01-01
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Series: | Antibiotics |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-6382/12/1/123 |