Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor
BackgroundMelanocortin-1 receptor (Mc1r), a key signaling receptor for melanogenesis, has been reported to mediate migration of B16F10 melanoma cells. Interestingly, this activity appears to be a part of the constitutive signaling of Mc1r.MethodsWe carried out small interfering RNA-mediated knock-do...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Korean Endocrine Society
2014-06-01
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Series: | Endocrinology and Metabolism |
Subjects: | |
Online Access: | http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-179.pdf |