Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor

BackgroundMelanocortin-1 receptor (Mc1r), a key signaling receptor for melanogenesis, has been reported to mediate migration of B16F10 melanoma cells. Interestingly, this activity appears to be a part of the constitutive signaling of Mc1r.MethodsWe carried out small interfering RNA-mediated knock-do...

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Bibliographic Details
Main Authors: Ikjoo Seong, Jaesang Kim
Format: Article
Language:English
Published: Korean Endocrine Society 2014-06-01
Series:Endocrinology and Metabolism
Subjects:
Online Access:http://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-29-179.pdf