Phase separation of SGS3 drives siRNA body formation and promotes endogenous gene silencing

Phase separation of SGS3 drives siRNA body formation and promotes endogenous gene silencing

Summary: The generation of small interfering RNA (siRNA) involves many RNA processing components, including SUPPRESSOR OF GENE SILENCING 3 (SGS3), RNA-DEPENDENT RNA POLYMERASE 6 (RDR6), and DICER-LIKE proteins (DCLs). Nonetheless, how these components are coordinated to produce siRNAs is unclear. He...

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Bibliographic Details
Main Authors: Huijuan Tan, Wentao Luo, Wei Yan, Jie Liu, Yalikunjiang Aizezi, Ruixue Cui, Ruijun Tian, Jinbiao Ma, Hongwei Guo
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722018897

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http://www.sciencedirect.com/science/article/pii/S2211124722018897

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