Targeting senescence as an anticancer therapy
Cellular senescence is a stress response elicited by different molecular insults. Senescence results in cell cycle exit and is characterised by multiple phenotypic changes such as the production of a bioactive secretome. Senescent cells accumulate during ageing and are present in cancerous and fibro...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-11-01
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Series: | Molecular Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1002/1878-0261.13312 |