Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans

Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans

The response to osmotic stress is a highly conserved process for adapting to changing environmental conditions. Prior studies have shown that hyperosmolarity by addition of sorbitol to the growth medium is sufficient to increase both chronological and replicative lifespan in the budding yeast, Sacc...

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Bibliographic Details
Main Authors: Devon eChandler-Brown, Haeri eChoi, Shirley ePark, Billie eOcampo, Shiwen eChen, Anna eLe, George eSutphin, Lara eShamieh, Erica eSmith, Matt eKaeberlein
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Genetics
Subjects:
Glycerol
Longevity
Sorbitol
Dietary restriction
osmotic stress response
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00316/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00316/full

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