Identification of Novel Mutations and Expressions of <i>EPAS1</i> in Phaeochromocytomas and Paragangliomas
Endothelial PAS domain-containing protein 1 (<i>EPAS1</i>) is an oxygen-sensitive component of the hypoxia-inducible factors (HIFs) having reported implications in many cancers by inducing a pseudo-hypoxic microenvironment. However, the molecular dysregulation and clinical significance o...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
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Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/11/11/1254 |