A cytomegalovirus inflammasome inhibitor reduces proinflammatory cytokine release and pyroptosis

Abstract In response to viral infection, cells can initiate programmed cell death (PCD), leading to a reduction in the release of viral progeny. Viruses have therefore evolved specific mechanisms to curb PCD. Cytomegaloviruses (CMVs) are sophisticated manipulators of cellular defenses and encode pot...

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Bibliographic Details
Main Authors: Yingqi Deng, Eleonore Ostermann, Wolfram Brune
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45151-z