Overexpression of microRNA-205-5p promotes cholangiocarcinoma growth by reducing expression of homeodomain-interacting protein kinase 3

Abstract The microRNA miR-205-5p has diverse effects in different malignancies, including cholangiocarcinoma (CCA), but its effects on CCA progression is unclear. Here we investigated the role and function of miR-205-5p in CCA. Three CCA cell lines and human serum samples were found to have much hig...

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Bibliographic Details
Main Authors: Aye Myat Mon, Kitti Intuyod, Sirinapha Klungsaeng, Apinya Jusakul, Thatsanapong Pongking, Worachart Lert-itthiporn, Vor Luvira, Chawalit Pairojkul, Tullayakorn Plengsuriyakarn, Kesara Na-Bangchang, Somchai Pinlaor, Porntip Pinlaor
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49694-x