Integrated systems immunology approach identifies impaired effector T cell memory responses as a feature of progression to severe dengue fever

Integrated systems immunology approach identifies impaired effector T cell memory responses as a feature of progression to severe dengue fever

Abstract Background Typical symptoms of uncomplicated dengue fever (DF) include headache, muscle pains, rash, cough, and vomiting. A proportion of cases progress to severe dengue hemorrhagic fever (DHF), associated with increased vascular permeability, thrombocytopenia, and hemorrhages. Progression...

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Bibliographic Details
Main Authors: Lisa J. Ioannidis, Stephanie I. Studniberg, Emily M. Eriksson, Suhendro Suwarto, Dionisius Denis, Yang Liao, Wei Shi, Alexandra L. Garnham, R. Tedjo Sasmono, Diana S. Hansen
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Journal of Biomedical Science
Subjects:
Dengue fever
Dengue hemorrhagic fever
Effector memory T cells
Non-classical monocytes
Online Access:https://doi.org/10.1186/s12929-023-00916-4

Internet

https://doi.org/10.1186/s12929-023-00916-4

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