Enhanced Donor Antigen Presentation by B Cells Predicts Acute Cellular Rejection and Late Outcomes After Transplantation

Enhanced Donor Antigen Presentation by B Cells Predicts Acute Cellular Rejection and Late Outcomes After Transplantation

Background. Enhanced B-cell presentation of donor alloantigen relative to presentation of HLA-mismatched reference alloantigen is associated with acute cellular rejection (ACR), when expressed as a ratio called the antigen presenting index (API) in an exploratory cohort of liver and intestine transp...

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Bibliographic Details
Main Authors: Chethan Ashokkumar, PhD, Mylarappa Ningappa, PhD, Vikram Raghu, MD, George Mazariegos, MD, Brandon W. Higgs, PhD, Paul Morgan, BS, Lisa Remaley, PAC, Tamara Fazzolare Martin, PAC, Pamela Holzer, BSN, Kevin Trostle, MBA, Qingyong Xu, PhD, Adriana Zeevi, PhD, James Squires, MD, Kyle Soltys, MD, Simon Horslen, MBChB, Ajai Khanna, MD, Armando Ganoza, MD, Rakesh Sindhi, MD, FACS
Format: Article
Language:English
Published: Wolters Kluwer 2024-03-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001589

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http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001589

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