Bioinformatic identification of hub genes Myd88 and Ccl3 and TWS-119 as a potential agent for the treatment of massive cerebral infarction

Bioinformatic identification of hub genes Myd88 and Ccl3 and TWS-119 as a potential agent for the treatment of massive cerebral infarction

BackgroundMassive cerebral infarction (MCI) causes severe neurological deficits, coma and can even result in death. Here, we identified hub genes and pathways after MCI by analyzing microarray data from a murine model of ischemic stroke and identified potential therapeutic agents for the treatment o...

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Bibliographic Details
Main Authors: Ai Guo, Bin Gao, Mengting Zhang, Xiaoyu Shi, Weina Jin, Decai Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Neuroscience
Subjects:
massive cerebral infarction
microarray
connectivity map
hub gene
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1171112/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2023.1171112/full

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