CRISPR/Cas9-mediated knockout of the Vanin-1 gene in the Leghorn Male Hepatoma cell line and its effects on lipid metabolism

CRISPR/Cas9-mediated knockout of the Vanin-1 gene in the Leghorn Male Hepatoma cell line and its effects on lipid metabolism

Objective Vanin-1 (VNN1) is a pantetheinase that catalyses the hydrolysis of pantetheine to produce pantothenic acid and cysteamine. Our previous studies have shown that the VNN1 is specifically expressed in chicken liver which negatively regulated by microRNA-122. However, the functions of the VNN1...

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Bibliographic Details
Main Authors: Lu Xu, Zhongliang Wang, Shihao Liu, Zhiheng Wei, Jianfeng Yu, Jun Li, Jie Li, Wen Yao, Zhiliang Gu
Format: Article
Language:English
Published: Asian-Australasian Association of Animal Production Societies 2024-03-01
Series:Animal Bioscience
Subjects:
chicken
crispr-cas9
liver metabolism
rna-seq
vnn1
Online Access:http://www.animbiosci.org/upload/pdf/ab-23-0162.pdf

Internet

http://www.animbiosci.org/upload/pdf/ab-23-0162.pdf

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