A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice

A xanthene derivative, DS20060511, attenuates glucose intolerance by inducing skeletal muscle-specific GLUT4 translocation in mice

Furuzono et al. identify DS20060511, a skeletal muscle cell-specific GLUT4 translocation enhancer. They find that DS20060511 have remarkable effects on lowering blood glucose and enhancing skeletal muscle glucose uptake via GLUT4, highlighting its potential as antidiabetic medicine.

Bibliographic Details
Main Authors: Shinji Furuzono, Tetsuya Kubota, Junki Taura, Masahiro Konishi, Asuka Naito, Masato Tsutsui, Hiroshi Karasawa, Naoto Kubota, Takashi Kadowaki
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02491-6

Internet

https://doi.org/10.1038/s42003-021-02491-6

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