Loss of mammalian glutaminase orthologs impairs sperm function in Caenorhabditis elegans

Summary: The decline in sperm function is a major cause of human male infertility. Glutaminase, a mitochondrial enzyme that catalyzes the hydrolysis of glutamine to generate glutamate, takes part in many diverse biological processes such as neurotransmission, metabolism, and cellular senescence. Her...

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Bibliographic Details
Main Authors: Qifei Liang, Haiyan Yang, Zhifei Zhang, Jialin C. Zheng, Zhao Qin
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223002833