Importance of the putative furin recognition site 742RNRR745 for antiangiogenic Sema3C activity in vitro

Angiogenesis is one of the key processes in the growth and development of tumors. Class-3 semaphorins (Sema3) are characterized as axon guidance factors involved in tumor angiogenesis by interacting with the vascular endothelial growth factor signaling pathway. Sema3 proteins convey their regulatory...

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Bibliographic Details
Main Authors: I. Valiulyte, V. Preitakaite, A. Tamasauskas, A. Kazlauskas
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001100610&lng=en&tlng=en