Variants in the zinc transporter-3 encoding gene (SLC30A3) in schizophrenia and bipolar disorder: Effects on brain glutamate–A pilot study

Variants in the zinc transporter-3 encoding gene (SLC30A3) in schizophrenia and bipolar disorder: Effects on brain glutamate–A pilot study

Zinc transporter 3 (ZnT3) has been implicated in the aetiopathology of schizophrenia. In this pilot study, we tested the hypothesis that the presence of a minor allele of two variants in the gene encoding ZnT3 (SLC30A3) affects brain glutamate and cognitive activity in patients with schizophrenia an...

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Bibliographic Details
Main Authors: Luke A. Jelen, Mark S. Green, Sinead King, Alex G. Morris, Xinyuan Zhang, David J. Lythgoe, Allan H. Young, Jacqueline De Belleroche, James M. Stone
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Psychiatry
Subjects:
glutamate
ZnT3
zinc transporter
MRS-1H nuclear magnetic resonance spectra
schizophrenia
bipolar (affective/mood) disorders
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.929306/full

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https://www.frontiersin.org/articles/10.3389/fpsyt.2022.929306/full

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