New Genetically Manipulated Mice Provide Insights Into the Development and Physiological Functions of Invariant Natural Killer T Cells

New Genetically Manipulated Mice Provide Insights Into the Development and Physiological Functions of Invariant Natural Killer T Cells

Invariant natural killer T (iNKT) cells are a unique T cell subset that exhibits characteristics of both innate immune cells and T cells. They express Vα14-Jα18 (Trav11-Traj18) as an invariant chain of the T cell receptor (TCR) and are restricted to the MHC class I-like monomorphic antigen presentin...

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Bibliographic Details
Main Authors: Yue Ren, Etsuko Sekine-Kondo, Midori Tateyama, Thitinan Kasetthat, Surasakadi Wongratanacheewin, Hiroshi Watarai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
invariant natural killer T cells
CD1d
Traj18
iPSC
obesity
adipose tissue
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01294/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.01294/full

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