In Vitro Evaluation of Curcumin- and Quercetin-Loaded Nanoemulsions for Intranasal Administration: Effect of Surface Charge and Viscosity

In Vitro Evaluation of Curcumin- and Quercetin-Loaded Nanoemulsions for Intranasal Administration: Effect of Surface Charge and Viscosity

The nose-to-brain delivery of neuroprotective natural compounds is an appealing approach for the treatment of neurodegenerative diseases. Nanoemulsions containing curcumin (CUR) and quercetin (QU) were prepared by high-pressure homogenization and characterized physicochemically and structurally. A n...

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Bibliographic Details
Main Authors: Gustavo Vaz, Adryana Clementino, Evgenia Mitsou, Elena Ferrari, Francesca Buttini, Cristina Sissa, Aristotelis Xenakis, Fabio Sonvico, Cristiana Lima Dora
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Pharmaceutics
Subjects:
curcumin
quercetin
electron paramagnetic resonance spectroscopy
central nervous system
nose-to-brain delivery
RPMI 2650
Online Access:https://www.mdpi.com/1999-4923/14/1/194

Internet

https://www.mdpi.com/1999-4923/14/1/194

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