Dynamic Changes of Behavioral Despair, HPA Axis Activity, and Hippocampal Neurogenesis in Male Rats Induced by Social Defeat Stress

Dynamic Changes of Behavioral Despair, HPA Axis Activity, and Hippocampal Neurogenesis in Male Rats Induced by Social Defeat Stress

Background: Psychosocial stress factors, such as threat and defeat, are major risk factors for the development of depression. The precise mechanisms underlying stress-induced depression are not clearly understood because the stress response in the brain varies in a stress-frequency-dependent manner....

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Bibliographic Details
Main Authors: Hiroyoshi Harada, Masayoshi Mori, Yusuke Murata, Shunsuke Kawanabe, Kazuki Terada, Taichi Matsumoto, Kenji Ohe, Munechika Enjoji
Format: Article
Language:English
Published: IMR Press 2023-02-01
Series:Journal of Integrative Neuroscience
Subjects:
depression
social defeat
stress frequency
hippocampal neurogenesis
hypothalamic-pituitary-adrenal axis
Online Access:https://www.imrpress.com/journal/JIN/22/2/10.31083/j.jin2202043

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https://www.imrpress.com/journal/JIN/22/2/10.31083/j.jin2202043

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