Reduced exercise capacity in patients with systemic sclerosis is associated with lower peak tissue oxygen extraction: a cardiovascular magnetic resonance-augmented cardiopulmonary exercise study

Abstract Background Exercise intolerance in systemic sclerosis (SSc) is typically attributed to cardiopulmonary limitations. However, problems with skeletal muscle oxygen extraction have not been fully investigated. This study used cardiovascular magnetic resonance (CMR)-augmented cardiopulmonary ex...

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Bibliographic Details
Main Authors: James T. Brown, Tushar Kotecha, Jennifer A. Steeden, Marianna Fontana, Christopher P. Denton, J. Gerry Coghlan, Daniel S. Knight, Vivek Muthurangu
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Journal of Cardiovascular Magnetic Resonance
Subjects:
Online Access:https://doi.org/10.1186/s12968-021-00817-1