HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2

HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2

High density lipoproteins (HDL) promote homeostasis and counteract stressful tissue damage that underlie cardiovascular and other diseases by mediating reverse cholesterol transport, reducing inflammation, and abrogating oxidative damage. However, metabolically stressful conditions associated with a...

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Bibliographic Details
Main Authors: Michael J. Trites, Brynne M. Stebbings, Hiroyuki Aoki, Sadhna Phanse, May G. Akl, Lei Li, Mohan Babu, Scott B. Widenmaier
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Physiology
Subjects:
HDL
liver stress defense
cholesterol
transcription factor
immunometabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1212785/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1212785/full

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