Dopamine transporter membrane mobility is bidirectionally regulated by phosphorylation and palmitoylation

Dopamine transporter membrane mobility is bidirectionally regulated by phosphorylation and palmitoylation

The primary regulator of dopamine availability in the brain is the dopamine transporter (DAT), a plasma membrane protein that drives reuptake of released dopamine from the extracellular space into the presynaptic neuron. DAT activity is regulated by post-translational modifications that establish cl...

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Bibliographic Details
Main Authors: Madhur Shetty, Danielle E. Bolland, Joshua Morrell, Bryon D. Grove, James D. Foster, Roxanne A. Vaughan
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Physiology
Subjects:
Fluorescence recovery after photobleaching
FRAP
Protein kinase C
Mitogen activated protein kinase
Palmitoyl acyl transferase
DHHC2
Online Access:http://www.sciencedirect.com/science/article/pii/S2665944123000093

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http://www.sciencedirect.com/science/article/pii/S2665944123000093

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