Dihydroartemisinin ameliorates cerebral I/R injury in rats via regulating VWF and autophagy-mediated SIRT1/FOXO1 pathway

Dihydroartemisinin ameliorates cerebral I/R injury in rats via regulating VWF and autophagy-mediated SIRT1/FOXO1 pathway

Dihydroartemisinin (DHA) has been found to inhibit the expression of von Willebrand factor (VWF), a marker of endothelial cell injury, but its mechanism in cerebral ischemia/reperfusion (I/R) injury remains obscure. In this study, I/R model was constructed through middle cerebral artery occlusion (M...

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Bibliographic Details
Main Authors: Duan Qi, Wu Junxia
Format: Article
Language:English
Published: De Gruyter 2023-07-01
Series:Open Medicine
Subjects:
cerebral ischemia/reperfusion injury
brain microvascular endothelial cells
dihydroartemisinin
von willebrand factor
sirt1/foxo1 pathway
autophagy
Online Access:https://doi.org/10.1515/med-2023-0698

Internet

https://doi.org/10.1515/med-2023-0698

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