Interplay between Gating and Block of Ligand-Gated Ion Channels

Drugs that inhibit ion channel function by binding in the channel and preventing current flow, known as channel blockers, can be used as powerful tools for analysis of channel properties. Channel blockers are used to probe both the sophisticated structure and basic biophysical properties of ion chan...

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Bibliographic Details
Main Authors: Matthew B. Phillips, Aparna Nigam, Jon W. Johnson
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/10/12/928