Peiminine Inhibits Glioblastoma in Vitro and in Vivo Through Cell Cycle Arrest and Autophagic Flux Blocking

Peiminine Inhibits Glioblastoma in Vitro and in Vivo Through Cell Cycle Arrest and Autophagic Flux Blocking

Background/Aims: Glioblastoma multiforme (GBM) is the most devastating and widespread primary central nervous system tumour in adults, with poor survival rate and high mortality rates. Existing treatments do not provide substantial benefits to patients; therefore, novel treatment strategies are requ...

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Bibliographic Details
Main Authors: Boxian Zhao, Chen Shen, Zhixing Zheng, Xiaoxiong Wang, Wenyang Zhao, Xin Chen, Fei Peng, Linmeng Xue, Mengting Shu, Xu Hou, Kaikai Wang, Chen Zhong, Jingxian Sun, Jinzhao Wan, Shiguang Zhao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Peiminine
GBM
Cell cycle
Autophagy
AKT-GSK3β
AMPK-ULK1
Online Access:https://www.karger.com/Article/FullText/495646

Internet

https://www.karger.com/Article/FullText/495646

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