A Metabolic Change towards Fermentation Drives Cancer Cachexia in Myotubes

Cachexia is a disorder associated with several pathologies, including cancer. In this paper, we describe how cachexia is induced in myotubes by a metabolic shift towards fermentation, and the block of this metabolic modification prevents the onset of the cachectic phenotype. Cachectic myotubes, obta...

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Bibliographic Details
Main Authors: Michele Mannelli, Tania Gamberi, Francesca Magherini, Tania Fiaschi
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/6/698