The function of BCL9 in Wnt/β-catenin signaling and colorectal cancer cells

<p>Abstract</p> <p>Background</p> <p>Most cases of colorectal cancer are initiated by hyperactivation of the Wnt/β-catenin pathway due to mutations in the APC tumour suppressor, or in β-catenin itself. A recently discovered component of this pathway is Legless, which is...

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Bibliographic Details
Main Authors: Worm Jesper, de la Roche Marc, Bienz Mariann
Format: Article
Language:English
Published: BMC 2008-07-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/199