Regulation of TGF-β Superfamily Signaling by SMAD Mono-Ubiquitination

TGF-β(transforming growth factor-β) superfamily signaling mediators are important regulators of diverse physiological and pathological events. TGF-β signals are transduced by transmembrane type I and type II serine/threonine kinase receptors and their downstream effectors, the SMAD(drosophila mother...

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Bibliographic Details
Main Authors: Feng Xie, Zhengkui Zhang, Hans van Dam, Long Zhang, Fangfang Zhou
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Cells
Subjects:
Online Access:http://www.mdpi.com/2073-4409/3/4/981