The Role of IRF8 Polymorphisms in Systemic Sclerosis Development and Pathogenesis

Systemic sclerosis (SSc) is a rare autoimmune disease whose molecular mechanisms are not yet fully understood. There is no definitive cure, and the main causes of death are pulmonary fibrosis and pulmonary arterial hypertension. Here, we focus on the interferon regulators factor 8 (IRF8), a factor i...

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Bibliographic Details
Main Authors: Anna Mennella, Giuseppe Ocone, Katia Stefanantoni, Loredana Frasca
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Journal of Molecular Pathology
Subjects:
Online Access:https://www.mdpi.com/2673-5261/5/1/8