Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter

Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter

N -Acetylneuraminic acid (Neu5Ac) is a negatively charged nine-carbon amino sugar that is often the peripheral sugar in human cell-surface glycoconjugates. Some bacteria scavenge, import, and metabolize Neu5Ac or redeploy it on their cell surfaces for immune evasion. The import of Neu5Ac by many bac...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Parveen Goyal, KanagaVijayan Dhanabalan, Mariafrancesca Scalise, Rosmarie Friemann, Cesare Indiveri, Renwick CJ Dobson, Kutti R Vinothkumar, Subramanian Ramaswamy
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: eLife Sciences Publications Ltd 2025-02-01
Σειρά:eLife
Θέματα:
TRAP transporter
Neu5Ac binding
Sodium ion
sialic acid transport
Fusobacterium
cryo-EM
Διαθέσιμο Online:https://elifesciences.org/articles/98158

Διαδίκτυο

https://elifesciences.org/articles/98158

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