Viral vectors based on bidirectional cell-specific mammalian promoters and transcriptional amplification strategy for use <it>in vitro </it>and <it>in vivo</it>

<p>Abstract</p> <p>Background</p> <p>Using cell-type-specific promoters to restrict gene expression to particular cells is an attractive approach for gene therapy, but often hampered by insufficient transcriptional activity of these promoters. Previous studies have show...

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Bibliographic Details
Main Authors: Kasparov Sergey, Paton Julian F, Liu Beihui
Format: Article
Language:English
Published: BMC 2008-05-01
Series:BMC Biotechnology
Online Access:http://www.biomedcentral.com/1472-6750/8/49