Protein aggregates are associated with replicative aging without compromising protein quality control

Differentiation of cellular lineages is facilitated by asymmetric segregation of fate determinants between dividing cells. In budding yeast, various aging factors segregate to the aging (mother)-lineage, with poorly understood consequences. In this study, we show that yeast mother cells form a prote...

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Bibliographic Details
Main Authors: Juha Saarikangas, Yves Barral
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/06197