Promotion of bone morphogenetic protein signaling by tetraspanins and glycosphingolipids.

Bone morphogenetic proteins (BMPs) belong to the transforming growth factor β (TGFβ) superfamily of secreted molecules. BMPs play essential roles in multiple developmental and homeostatic processes in metazoans. Malfunction of the BMP pathway can cause a variety of diseases in humans, including canc...

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Main Authors: Zhiyu Liu, Herong Shi, Lindsey C Szymczak, Taner Aydin, Sijung Yun, Katharine Constas, Arielle Schaeffer, Sinthu Ranjan, Saad Kubba, Emad Alam, Devin E McMahon, Jingpeng He, Neta Shwartz, Chenxi Tian, Yevgeniy Plavskin, Amanda Lindy, Nimra Amir Dad, Sunny Sheth, Nirav M Amin, Stephanie Zimmerman, Dennis Liu, Erich M Schwarz, Harold Smith, Michael W Krause, Jun Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4433240?pdf=render