The intergenic small non-coding RNA ittA is required for optimal infectivity and tissue tropism in Borrelia burgdorferi.

Post-transcriptional regulation via small regulatory RNAs (sRNAs) has been implicated in diverse regulatory processes in bacteria, including virulence. One class of sRNAs, termed trans-acting sRNAs, can affect the stability and/or the translational efficiency of regulated transcripts. In this study,...

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Bibliographic Details
Main Authors: Diana N Medina-Pérez, Beau Wager, Erin Troy, Lihui Gao, Steven J Norris, Tao Lin, Linden Hu, Jenny A Hyde, Meghan Lybecker, Jon T Skare
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-05-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008423